具有微纳加工、流体力学或光学工程相关专业硕士或博士学位，具有坚实的实验和理论基础。

主要从事功能核酸筛选、生物分子互作、细胞光学测量等相关研究工作。

工作勤勉、积极思考，敢于探索未知领域、勇于创新。

技术员：

工资及福利待遇：博士年薪20万-35万元（含学校、课题组的待遇），首个聘期2-3年；硕士年薪7-10万元；

课题组提供良好的科研环境，鼓励并全力支持博士后申报国家自科基金等项目；

入站博士后享有租住博士后公寓（或租房补贴1800元/月）以及长沙市购房补贴（按政策执行）；

入站博士后享受湖南大学教职工子女入托（省示范幼儿园）、入学（双语实验小学及中学）同等待遇；

在站期间，博士后经评审后可认定为副研究员、研究员；

博士后期间业绩优秀者可聘为教学科研岗位（副教授、教授）等职务。

有意者请将个人简历发到futinghnu@hnu.edu.cn

湖南大学分子科学与生物医学实验室 （MBL）于2010年10月正式成立，由中国科学院谭蔚泓院士任学术带头人，是一个跨院系的新型交叉学科研究机构，实验室主要成员来自化学与化工学院和生物学院，全部核心研究人员均具有海外研究经历。实验室现有中科院院士1人，教授7人，其他科研及管理人员6人，在站博士后13人，师生总人数逾110人。实验室以化学学科为基础，利用化学生物传感与计量学国家重点实验室的研究优势，结合自身在分子科学、材料科学、生物学和纳米技术等领域的研究优势，设计合成新的分子工具，用于分子医学的难点和前沿研究，力求为分子医学和转化医学的更深入发展提供一个革命性的科学研究和技术交流平台。

主要研究方向有化学生物学、生命分析化学、功能材料与纳米科学、分子医学等。具体研究内容包括：发展化学生物传感新方法和新技术，设计和开发新型功能纳米材料和分子探针；开展分子医学的基础和应用研究，实现重大疾病相关生物分子的高灵敏检测及早期诊断；借助生物分析和功能纳米材料的方法和手段，整合分子生物学、基因组学和蛋白质组学的技术，搭建多学科交叉研究平台，寻找对恶性肿瘤的早期诊断、治疗及预后有指导意义的分子标志物和分子靶标；促进基础研究与临床应用的紧密结合，为转化医学和个体化医疗提供革命性的分子工具。

实验室拥有流式细胞仪，DNA合成仪，激光共聚焦显微镜，Zeta电位仪，半制备色谱等一流的生化分析及生物医学研究所需的仪器设备；化学生物传感与计量学国家重点实验室（湖南大学）拥有包括双光子激光共聚焦显微镜、生物点样仪、高分辨生物质谱、生物拉曼成像系统、原子力显微镜等一系列大型专业仪器；生物学院拥有动物房、小动物成像系统、活细胞成像仪等生物医学研究相关仪器设备和平台。实验室力求把自身建成具有国际前沿水平的学术研究平台和技术交流平台，加强化学、生物学、材料学、生物医学等学科的交叉与融合，积极培养高级复合型人才，并推动实验技术与成果的产业化。欢迎具有相关专业知识及立志于化学创新创业做出卓越贡献的研究人员加入MBL。

MBL博士后获基金资助情况

2019年代表性论文：

1.Jie Tan, Hao Li, Xiaoxiao Hu, Razack Abdullah, Sitao Xie, Lili Zhang, Mengmeng Zhao, Qiang Luo, Yazhou Li, Zhijun Sun, Quan Yuan*, and Weihong Tan*, Size-tunable assemblies based on ferrocene-containing DNA polymers for spatially uniform penetration, Chem, 5, 1775-1792, 2019.

2.Yifan Lyu, Yian Guo, Ren Cai, Ruizi Peng, Chengyi Hong, Xigao Chen, Weijia Hou, Xiaowei Li, Jie Tan, Yuxiu Zou, Xiaobing Zhang, Qiaoling Liu, Weihong Tan*, Spherically directed synthesis and enhanced cellular internalization of metal-crosslinked DNA micelles, Chem, 5, 913-928, 2019.

3.Jin Li, Kanyu Xun, Ke Pei, Xiaojing Liu, Xueyu Peng, Yulin Du, Liping Qiu*, Weihong Tan*, A cell membrane-anchored DNA nano-platform for programming cellular interactions, Journal of the American Chemical Society, 2019.

4.Fang Zhou, Ting Fu, Qin Huang, Hailan Kuai, Liuting Mo, Honglin Liu, Qianqian Wang, Yongbo Peng, Dongmei Han, Zilong Zhao*, Xiaohong Fang*, Weihong Tan*, Hypoxia-activated PEGylated aptamer/antibody for cancer imaging with improved specificity, Journal of the American Chemical Society, 2019.

5.Long Li, Xigao Chen, Cheng Cui, Xiaoshu Pan, Xiaowei Li, Hoda Safari Yazd, Qiong Wu, Liping Qiu, Juan Li*, Weihong Tan*, Aptamer displacement reaction from live-cell surfaces and its applications, Journal of the American Chemical Society, 2019.

6.Xu Chang, Chao Zhang, Cheng Lv, Yang Sun, Mingzhi Zhang, Yumeng Zhao, Linlin Yang, Da Han*, Weihong Tan*, Construction of a multiple-aptamer-based DNA logic device on live cell membranes via associative toehold activation for accurate cancer cell identification, Journal of the American Chemical Society, 141, 12738-12743, 2019.

7.Yuan Liu, Yu Yang, Yujia Sun, Jibin Song, Nicholas Rudawski, Xiaoyuan Chen, Weihong Tan*, Ostwald ripening-mediated grafting of metal-organic frameworks on a single colloidal nanocrystal to form uniform and controllable MXF, Journal of the American Chemical Society, 141, 7407-7413, 2019.

8.Hui Liu, Qiuxia Yang, Ruizi Peng, Hailan Kuai, Yifan Lyu, Xiaoshu Pan, Qiaoling Liu*, Weihong Tan*, Artificial signal feedback network mimicking cellular adaptivity, Journal of the American Chemical Society, 141 (16), 6458-6461, 2019.

9.Lili Zhang, Razack Abdullah, XiaoXiao Hu, Huarong Bai, Huanhuan Fan, Lei He, Hao Liang, Jianmei Zou, Yanlan Liu, Yang Sun, Xiaobing Zhang*, and Weihong Tan*, Engineering of bioinspired, size-controllable and self-degradable cancertargeting DNA nanoflowers via incorporation of an artificial sandwich base, Journal of the American Chemical Society, 141(10),4282-4290, 2019.

10.Ren Cai#, Dan Yang#, Keng-Te Lin, Yifan Lyu, Bowen Zhu, Zhen He, Lili Zhang, Yusuke Kitamura, Liping Qiu, Yuliang Zhao, Zhuo Chen*, Weihong Tan*, Generalized preparation of 2D quasi-nanosheets via self-assembly of nanoparticles, Journal of the American Chemical Society, 141(4),1725-1734, 2019.

11.Jie Tan, Mengmeng Zhao, Jie Wang, Zhihao Li, Ling Liang, Liqin Zhang, Quan Yuan,* and Weihong Tan*, Regulation of protein activity and cellular functions mediated by molecularly evolved nucleic acids, Angewandte Chemie International Edition, 58, 1621-1625, 2019.

12.Cheng Jin, Jiaxuan He, Jianmei Zou, Wenjing Xuan, Ting Fu, Ruowen Wang,  Weihong Tan*, Phosphorylated lipid-conjugated oligonucleotide selectively anchors on cell membranes with high alkaline phosphatase expression, Nature Communications, 2019.

13.Dailiang Zhang, Miaomiao Hu, Xi Yuan, Yongxiang Wu, XiaoXiao Hu, Shuai Xu, Hong-Wen Liu, XiaoBing Zhang, Yanlan Liu*, Weihong Tan*, Engineering self-calibrating nanoprobe with two-photon activated fluorescence resonance energy transfer for ratiometric imaging of biological selenocysteine, ACS Applied Materials & Interfaces, 2019.

14.Jianmei Zou, Muling Shi, Xiaojing Liu, Cheng Jin, Xiaojing Xing, Liping Qiu*, and Weihong Tan, Aptamer-functionalized exosomes: elucidating the cellular uptake mechanism and the potential for cancer-targeted chemotherapy, Analytical Chemistry, 91 (3), 2425-2430, 2019.

15.Chao Liu#, Wei Jiang#, Xibin Tian#, Peng Yang, Le Xiao, Jianglin Li, Liping Qiu, Haijun Tu*, Weihong Tan*, Identification of Vigilin as a potential ischemia biomarker by brain slice-based SELEX, Analytical Chemistry, 2019.

16.Razack Abdullah#, Sitao Xie#, Ruowen Wang*, Cheng Jin, Yulin Du, Ting Fu, Juan Li, Jie Tan, Lili Zhang, and Weihong Tan*, Artificial sandwich base for monitoring single-nucleobase changes and charge-transfer rates in DNA，Analytical Chemistry, 91, 2074-2078, 2019.

17.Mengyi Xiong, Qiming Rong, Gezhi Kong, Chan Yang, Yan Zhao, Feng-Li Qu*, Xiao-Bing Zhang*, Weihong Tan*, Hybridization chain reaction-based nanoprobe for cancer cell recognition and amplified photodynamic therapy, Chem. Commun., 55, 3065-3068, 2019.

18.Ding Ding, Yinling Zhang, Edward A. Sykes, Long Chen, Zhuo Chen*, and Weihong Tan*, The influence of physiological environment on the targeting effect of aptamer-guided gold nanoparticles, Nano Research, 12(1): 129-135, 2019.

19.Shuai Xu#, Hong-Wen Liu#, Xia Yin, Lin Yuan, Shuang-Yan Huan*, Xiao-Bing Zhang*, A cell membrane-anchored fluorescent probe for monitoring carbon monoxide release from living cells, Chemical Communications, 2019.

20.Jun-Bin Li, Qianqian Wang, Hong-Wen Liu, Xia Yin,* Xiao-Xiao Hu, Lin Yuan, Xiao-Bing Zhang *, Engineering of a bioluminescent probe for imaging nitroxyl in live cells and mice, Chemical Communications, 55, 1758-1761, 2019.

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