北京理工大学化学与化工学院王蔚芝课题组主要从事生命分析检测、纳米生物医学与靶向活体分子影像研究。现拟招收博士后及研究生, 欢迎相关专业学子加入研究团队。

1. 博士后应聘条件：基础知识扎实，刻苦努力，有团队合作精神；身体健康，具有良好的沟通能力；具有医学、化学、材料学相关背景。博士后工资待遇按照北京理工大学相关规定执行（15-35万）并根据科研成果提供业绩津贴。入站博士后可申请博士后创新人才支持计划，国家自然科学基金项目、博管会面上项目，特别资助项目等。

2.课题组长期招收硕、博士研究生，联合培养研究生及热爱科研的本科生，优先考虑基础知识扎实，刻苦努力，勤奋好学，矢志科研者，工资另议。

请有意者将个人简历（包括学习工作经历、代表论文等）发送至邮箱：wangwz@bit.edu.cn

王蔚芝，北京理工大学化学与化工学院特别研究员，副教授，博士生导师。2006年本科毕业于北京理工大学，2011年博士毕业于中科院化学所（师从马会民研究员和赵睿研究员），随后进入国家纳米科学中心工作。2016-2017年在美国斯坦福大学从事科研工作，师从Hongjie Dai教授。2019年7月加入北京理工大学。王蔚芝博士以亲和多肽为主要研究工具，构筑生物分子相互作用、识别、筛选和自组装体系。在针对细胞、体液、活体的精准化学测量和针对肿瘤的靶向诊疗等方面取得系列成果。近年已在SCI期刊发表论文30余篇，包括Advanced Materials，Analytical Chemistry，Biomaterials，Lab on a Chip，Theranostics，Chemical Communications等。2015年入选北京市优秀人才培养“青年拔尖”个人。2019年入选中国科学院青年创新促进会。主持国家自然科学基金项目、北京市自然科学基金项目等。

详细介绍参见学院网站：http://cce.bit.edu.cn/docs/20190830102320452073.pdf

代表性论文：

1、Weizhi Wang*, Zhiyuan Hu*, Targeting Peptide-based Probes for Molecular Imaging and Diagnosis. Advanced Materials 2018, 30: 1804827.

2、Weizhi Wang#, Zhuoran Ma#, Shoujun Zhu, Hao Wan, Jingying Yue, Huilong Ma, Rui Ma, Qinglai Yang, Zihua Wang, Qian Li, Yixia Qian, Chunyan Yue, Yuehua Wang, Linyang Fan, Yeteng Zhong, Ying Zhou, Hongpeng Gao, Junshan Ruan, Zhiyuan Hu*, Yongye Liang*, Hongjie Dai*. Molecular cancer imaging in the second near-infrared window using a renal-excreted NIR-II fluorophore-peptide probe. Advanced Materials 2018, 30: 1800106.

3、Yuehua Wang, Fei Jia, Zihua Wang, Yixia Qian, Linyang Fan, He Gong, Aiqin Luo, Jian Sun, Zhiyuan Hu, Weizhi Wang*. Boosting the theranostic effect of liposomal probes toward prominin-1 through optimized dual-site targeting. Analytical Chemistry 2019, 91: 7245.

4、Yixia Qian, Yuehua Wang, Fei Jia, Zihua Wang, Chunyan Yue, Weikai Zhang, Zhiyuan Hu, Weizhi Wang*. Tumor-microenvironment controlled nanomicelles with AIE property for boosting cancer therapy and apoptosis monitoring. Biomaterials 2019, 188: 96.

5、Zihua Wang, Yuehua Wang, Xiangqian Jia, Qiuju Han, Yixia Qian, Qian Li, Junfeng Xiang, Qian Wang, Zhiyuan Hu and Weizhi Wang*. MMP-2-Controlled Transforming Micelles for Heterogeneic Targeting and Programmable Cancer Therapy. Theranostics 2019, 9: 1728.

6、Weizhi Wang#, Zewen Wei#, Di Zhang, Huailei Ma, Zihua Wang, Xiangli Bu, Menglin Li, Leroy Hood, Lingling Geng, Christopher Lausted, Qiaojun Fang, Hao Wang*, Zhiyuan Hu*. Rapid screening of peptide probes through in situ single bead sequencing microarray. Analytical Chemistry 2014, 86: 11854.

7、Weizhi Wang#, Menglin Li#, Zewen Wei, Zihua Wang, Xiangli Bu, Wenjia Lai, Shu Yang, He Gong, Hui Zheng, Yuqiao Wang, Ying Liu, Qin Li*, Qiaojun Fang*, Zhiyuan Hu*. Bimodal imprint chips for peptide screening: integration of high-throughput sequencing by MS and affinity analyses by Surface Plasmon Resonance imaging. Analytical Chemistry 2014, 86: 3703.

8、Zihua Wang#, Weizhi Wang#*, Xiangli Bu, Zewen Wei, Lingling Geng, Yue Wu, Chengyan Dong, Liqiang Li, Di Zhang, Shu Yang, Fan Wang, Christopher Lausted, Leroy Hood, Zhiyuan Hu*. Microarray based screening of peptide nano probes for HER2 positive tumor. Analytical Chemistry 2015, 87: 8367.

9、Weizhi Wang*#, Zihua Wang#, Xiangli Bu, Ren Li, Zhiyuan Hu*. Discovering of tumor-targeting peptides using bi-functional microarray. Advanced Healthcare Materials 2015, 4: 2802.

10、Weizhi Wang, Yanyan Huang, Yulong Jin, Yunfeng Xie, Rui Zhao*, Shaoxiang Xiong, Guoquan Liu, Yi Chen, Huimin Ma. Integrated SPPS on continuous-flow radial microfluidic chip. Lab on a Chip 2011, 11: 929.

11、Yixia Qian#, Weizhi Wang#*, Zihua Wang, Qiuju Han, Xiangqian Jia, Shu Yang, Zhiyuan Hu*. Switchable probes: pH-triggered and VEGFR2 targeted peptides screening through imprinting microarray. Chemical Communications 2016, 52: 5690.

12、Yixia Qian#, Weizhi Wang#*, Zihua Wang, Xiangqian Jia, Qiuju Han, Iman Rostami, Yuehua Wang, Zhiyuan Hu*. pH-triggered peptide self-assembly for targeting imaging and therapy toward angiogenesis with enhanced signals. ACS Applied Materials & Interfaces 2018, 10: 7871.

13、Qiuju Han#, Weizhi Wang#*, Xiangqian Jia, Yixia Qian, Qian Li, Zihua Wang, Weikai Zhang, Shu Yang, Yunhong Jia*, Zhiyuan Hu*. Switchable liposomes: targeting-peptide-functionalized and pH-triggered cytoplasmic delivery. ACS Applied Materials & Interfaces 2016, 8: 18658.

14、Zihua Wang#, Weizhi Wang#*, Lingling Geng, Zhiyuan Hu*. Distinguishing of tumor cell-targeting peptide ligands through a color-encoding microarray. Lab on a Chip 2015, 15: 4512.

15、Yuehua Wang, Zihua Wang, Yixia Qian, Linyang Fan, Chunyan Yue, Fei Jia, Jian Sun*, Zhiyuan Hu*, Weizhi Wang*. Synergetic Estrogen receptor-targeting liposome nanocarriers with anti-phagocytic property for enhanced tumors theranostics. Journal of Materials Chemistry B, 2019, 7: 1056.

16、Qiuju Han, Xiangqian Jia, Yixia Qian, Zihua Wang, Shu Yang, Yunhong Jia*, Weizhi Wang*, Zhiyuan Hu*. Peptide functionalized targeting liposomes: for nanoscale drug delivery towards angiogenesis. Journal of Materials Chemistry B 2016, 4: 7087.

17、Xiangqian Jia#, Weizhi Wang#*, Qiuju Han, Zihua Wang, Yunhong Jia*, Zhiyuan Hu*. Micromixer based preparation of functionalized liposomesand targeting drug delivery. ACS Medicinal Chemistry Letters 2016, 7: 429.

18、Lingling Geng, Zihua Wang, Xiangqian Jia, Qiuju Han, Zhichu Xiang, Dan Li, Xiaoliang Yang, Di Zhang, Xiangli Bu, Weizhi Wang*, Zhiyuan Hu*, Qiaojun Fang*. HER2 targeting peptides screening and applications in tumor imaging and drug delivery. Theranostics 2016, 6: 1261.

19、Hui Zheng#, Weizhi Wang#, Xiaojun Li, Zihua Wang, Leroy Hood, Christopher Lausted, Zhiyuan Hu*. Automated Teflon microfluidic peptide synthesizer. Lab on a Chip 2013, 13: 3347.

20、Zhuoran Ma#, Hao Wan#, Weizhi Wang#, Xiaodong Zhang, Takaaki Uno, Qianglai Yang, Jingying Yue, Hongpeng Gao, Yeteng Zhong, Ye Tian, Qinchao Sun, Yongye Liang, Hongjie Dai*. A theranostic agent for cancer therapy and imaging in the second near-infrared window. Nano Research 2019, 12: 273.